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Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice
The present study investigated the prophylactic influence of melatonin against cyclophosphamide-induced oxidative stress in mouse tissues. Lipid peroxidation, reduced glutathione (GSH), glutathione disulphide (GSSG), glutathione peroxidase (GSH-Px) and …Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice Lipid peroxidation, reduced glutathione (GSH), glutathione disulphide (GSSG), glutathione peroxidase (GSH-Px) and serum phosphatase levels were analyzed in brain, spleen liver, lungs, kidney and testes.Because melatonin has excellent antioxidative properties, there is a likely possibility that melatonin would protect against the toxicity of cyclophosphamide; that is, an elevated level of melatonin in body may act as a prophylactic against hepatic damage. Thus, the aim of this study was to determine if melatonin has hepatoprotective effects. Histological examination of liver tissues was also used to …An ethanolic extract of Origanum vulgare attenuates cyclophosphamide-induced pulmonary injury and oxidative lung damage in mice Pharm Biol 2014;52:1229–1236. Google Scholar 41…. Formulation, Reverses Cyclophosphamide-Induced … Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice.list of citation(s) prophylactic action of melatonin against cyclophosphamideinduced oxidative stress in micelist of citation(s) prophylactic action of melatonin against cyclophosphamideinduced oxidative stress in mice… Formulation, Reverses Cyclophosphamide-Induced … Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice.Cyclophosphamide has been reported to induce oxidative stress in mice (Manda and Bhatia 2003 Manda K., Bhatia A. L. Prophylactic action of melatonin against cyclophosphamide–induced oxidative stress …The markers of oxidative stress including malondialdehyde content, protein carbonyl content, protein thiol, reduced glutathione and myeloperoxidase activity, a marker of neutrophil infiltration, were measured in kidney homogenates.